He developed several treatments for knights, most notably for an infliction called " Fistula In Ano, " a condition where a large, painful lump appears between the base of the hemlock, opium and henbane in 1376.
2.
Arderne recommended opium as a soporific and as an external anesthetic that the patient schal slepe so that he schal fele no kuttyng .'In his document about Fistula in ano, John of Arderne sets out not only his operative procedures but also his code of conduct for the ideal medical practitioner.
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